Quarterly report pursuant to Section 13 or 15(d)

Collaborative Arrangements - Merck Sitagliptin Catalyst Supply Agreement (Details)

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Collaborative Arrangements - Merck Sitagliptin Catalyst Supply Agreement (Details) - USD ($)
$ in Thousands
1 Months Ended 3 Months Ended 9 Months Ended
Dec. 31, 2015
Feb. 29, 2012
Sep. 30, 2020
Sep. 30, 2019
Sep. 30, 2020
Sep. 30, 2019
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]            
Revenue recognized     $ 18,385 $ 21,906 $ 48,023 $ 49,808
Merck [Member] | Supply Agreement [Member]            
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]            
Term of collaborative research and development agreement   5 years        
Optional extension period 5 years          
Merck [Member] | Supply Agreement [Member] | Product Revenue [Member]            
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]            
Revenue recognized     $ 3,200 $ 3,600 $ 7,000 $ 11,400