Quarterly report pursuant to Section 13 or 15(d)

Balance Sheets Details - Property and Equipment, net (Details)

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Balance Sheets Details - Property and Equipment, net (Details) - USD ($)
$ in Thousands
Sep. 30, 2020
Dec. 31, 2019
Property, Plant and Equipment [Line Items]    
Property and equipment $ 40,522 $ 39,533
Less: accumulated depreciation and amortization (33,233) (33,251)
Property and equipment, net 7,289 6,282
Laboratory equipment [Member]    
Property, Plant and Equipment [Line Items]    
Property and equipment 24,837 23,561
Leasehold improvements [Member]    
Property, Plant and Equipment [Line Items]    
Property and equipment 10,774 10,804
Computer equipment and software [Member]    
Property, Plant and Equipment [Line Items]    
Property and equipment 3,134 3,016
Office equipment and furniture [Member]    
Property, Plant and Equipment [Line Items]    
Property and equipment 1,175 1,461
Construction in progress [Member]    
Property, Plant and Equipment [Line Items]    
Property and equipment $ 602 $ 691