Annual report pursuant to Section 13 and 15(d)

Consolidated Statements of Operations

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Consolidated Statements of Operations (USD $)
In Thousands, except Per Share data, unless otherwise specified
12 Months Ended
Dec. 31, 2012
Dec. 31, 2011
Dec. 31, 2010
Revenues:      
Product $ 35,924 $ 49,021 $ 32,835
Collaborative research and development 50,127 71,368 70,196
Government awards 2,247 3,476 4,073
Total revenues 88,298 123,865 107,104
Costs and operating expenses:      
Cost of product revenues 30,647 41,781 27,982
Research and development 56,785 61,049 52,405
Selling, general and administrative 31,379 36,942 33,841
Total costs and operating expenses 118,811 139,772 114,228
Loss from operations (30,513) (15,907) (7,124)
Interest income 252 273 166
Interest expense and other, net (326) (675) (1,199)
Loss before provision for income taxes (30,587) (16,309) (8,157)
Provision for income taxes 270 241 384
Net loss $ (30,857) $ (16,550) $ (8,541)
Net loss per share of common stock, basic and diluted (dollars per share) $ (0.84) $ (0.46) $ (0.35)
Weighted average common shares used in computing net loss per share of common stock, basic and diluted (shares) 36,768 35,674 24,594